Abstract: Up to 50% of colorectal cancer (CRC) patients develop colorectal liver metastases (CRLM).
The aim of this study was to gauge the awareness and perception of liver transplantation (LT) for
non-resectable CRLM, and to describe the current referral patterns and management strategies for
CRLM in Canada. Surgeons who provide care for patients with CRC were invited to an online survey
through the Canadian Association of General Surgeons, the Canadian Society of Colon and Rectal
Surgeons, and the Canadian Society of Surgical Oncology. Thirty-seven surveys were included. The
most utilized management strategy for CRLM was to refer to a hepatobiliary surgeon for assessment
of metastectomy (78%), and/or refer to medical oncologists for consideration of chemotherapy (73%).
Among the respondents, 84% reported that their level of knowledge about LT for CRLM was low, yet
the perception of exploring the option of LT for non-resectable CRLM seemed generally favorable
(81%). The decision to refer for consideration of LT for CRLM treatment seemed to depend on
patient-specific factors and the local hepatobiliary surgeon’s recommendation. Providing CRC care
providers with educational materials on up-to-date CRLM management may help raise the awareness
of the use of LT for non-resectable CRLM