Bucharest Pancreatic Fest 2024, 6 -7 septembrie 2024
Bucharest Pancreatic Fest 2024 Bucharest PancreaticFest, principalul eveniment educațional în pancreatologie din România, a ajuns la ediția a 12-a a EUS Workshop for Pancreatic Pathology și la ediția a 11-a a Cursului de Boli Pancreatice. Bucharest PancreaticFest 2024 se va desfășura, ca în anii anteriori, la Hotel Crowne Plaza din București, pe 6 și 7 septembrie. Formatul evenimentului rămâne neschimbat: prima zi va fi dedicată Atelierului EUS pentru bolile pancreatice, iar a doua zi va fi rezervată Cursului de [...]
Guidelines for Perioperative Care for Pancreatoduodenectomy: Enhanced Recovery After Surgery (ERAS) Recommendations 2019
Background Enhanced recovery after surgery (ERAS) pathways are now implemented worldwide with strong evidence that adhesion to such protocol reduces medical complications, costs and hospital stay. This concept has been applied for pancreatic surgery since the first published guidelines in 2012. This study presents the updated ERAS recommendations for pancreatoduodenectomy (PD) based on the best available evidence and on expert consensus. Methods A systematic literature search was conducted in three databases (Embase, Medline Ovid and Cochrane Library Wiley) for [...]
Deciphering the Etiology of Weight Loss Following Pancreatectomy
Recurrence rates after resection for pancreatic cancer are high, with >70% of patients developing recurrence within 1 year following their index operation.1 While guidelines recommend close surveillance with cross-sectional imaging every 3–6 months postoperatively for the first 2 years, population-level studies show that only 40% of patients actually undergo imaging surveillance by the 2-year mark.2 Additionally, the current gold-standard serum biomarker, carbohydrate antigen (CA) 19-9, is not synthesized in 10% of patients and is normal in another one-third of patients, limiting its clinical [...]
Proposal for a New Pathologic Prognostic Index After Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma (PINC)
Background Limited information is available on the relevant prognostic variables after surgery for patients with pancreatic ductal adenocarcinoma (PDAC) subjected to neoadjuvant chemotherapy (NACT). NACT is known to induce a spectrum of histological changes in PDAC. Different grading regression systems are currently available; unfortunately, they lack precision and accuracy. We aimed to identify a new quantitative prognostic index based on tumor morphology. Patients and Methods The study population was composed of 69 patients with resectable or borderline resectable PDAC treated [...]
Deciphering the Etiology of Weight Loss Following Pancreatectomy
Recurrence rates after resection for pancreatic cancer are high, with >70% of patients developing recurrence within 1 year following their index operation.1 While guidelines recommend close surveillance with cross-sectional imaging every 3–6 months postoperatively for the first 2 years, population-level studies show that only 40% of patients actually undergo imaging surveillance by the 2-year mark.2 Additionally, the current gold-standard serum biomarker, carbohydrate antigen (CA) 19-9, is not synthesized in 10% of patients and is normal in another one-third of patients, limiting its clinical [...]
Proposal for a New Pathologic Prognostic Index After Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma (PINC)
Background Limited information is available on the relevant prognostic variables after surgery for patients with pancreatic ductal adenocarcinoma (PDAC) subjected to neoadjuvant chemotherapy (NACT). NACT is known to induce a spectrum of histological changes in PDAC. Different grading regression systems are currently available; unfortunately, they lack precision and accuracy. We aimed to identify a new quantitative prognostic index based on tumor morphology. Patients and Methods The study population was composed of 69 patients with resectable or borderline resectable PDAC treated [...]