Textbook of Liver Transplantation – A Multidisciplinary Approach
Liver transplantations require a complex and varied, multidisciplinary approach involving not only hepatologists and surgeons but also pathologists, psychologists, professional educators, nurses and, in the case of young patients, also pediatricians and development experts. This textbook provides an overview of the management problems involved in liver transplantation for acute and chronic liver disease, pediatric liver transplantation and the psychosocial aspects of liver transplantation. A closing chapter, focusing on the developments and future prospects in liver transplantation, outlines the potential offered [...]
Current practice of normothermic regional perfusion and machine perfusion in donation after circulatory death liver transplants in Italy
Background Normothermic regional perfusion (NRP) and machine perfusion (MP) are variously used in many European centers to improve the outcomes after liver transplantation from donation after circulatory death (DCD). In Italy, a combination of NRP and subsequent MP has been used since the start of the activity. While NRP is mandatory for every DCD recovery, the subsequent use of MP is left to each center. Methods We have designed a national survey to investigate practices and policies of these techniques. [...]
National experience with living donor liver transplantation for hepatocellular carcinoma
Living donor liver transplantation (LDLT) is an attractive option to decrease waitlist dropout, particularly for patients with hepatocellular carcinoma (HCC) who face lengthening waiting times. Using the United Network for Organ Sharing (UNOS) national database, trends in LDLT utilization for patients with HCC were evaluated, and post-LT outcomes for LDLT versus deceased donor liver transplantation (DDLT) were compared. From 1998 to 2018, LT was performed in 20,161 patients with HCC including 726 (3.6%) who received LDLT. The highest LDLT utilization [...]
Surgical Complications After Liver Transplantation (Vascular and Biliary)
Complications after liver transplantation primarily affect the vasculature of the liver and the bile ducts. While these complications are rare, their impact on morbidity and mortality for the transplant recipient may be serious. Careful pre-transplant assessment of the vascular supply of the liver and bile ducts may help preventing these complications. Vascular complications include hepatic artery stenosis and thrombosis, portal vein stenosis and thrombosis, vena cava stenosis and splenic artery steal syndrome. Bile leakage is the most common biliary complication, [...]
Textbook of Liver Transplantation – A Multidisciplinary Approach
Liver transplantations require a complex and varied, multidisciplinary approach involving not only hepatologists and surgeons but also pathologists, psychologists, professional educators, nurses and, in the case of young patients, also pediatricians and development experts. This textbook provides an overview of the management problems involved in liver transplantation for acute and chronic liver disease, pediatric liver transplantation and the psychosocial aspects of liver transplantation. A closing chapter, focusing on the developments and future prospects in liver transplantation, outlines the potential offered [...]
Percutaneous transhepatic treatment for biliary stricture after duct-to-duct biliary anastomosis in living donor liver transplantation: a 9-year single-center experience
Objectives To investigate clinical outcomes of percutaneous transhepatic treatment for biliary stricture after duct-to-duct biliary anastomosis in living donor liver transplantation (LDLT). Methods This retrospective study examined baseline characteristics, procedural details, clinical outcomes, drainage catheter removal rate within 8 months, and recurrence after catheter removal using patients’ medical records and images. Risk factors for failure of drainage catheter removal within 8 months and recurrence of biliary stricture after drainage catheter removal were assessed via univariable and multivariable analyses. Results A [...]